Best Ergonomic Mouse for Pain in the Wrist


Best ergonomic mouse for wrist pain

As an Amazon Associate, I earn from qualifying purchases.
Updated: 07/21/2022

If you suffer from wrist pain or CTS (carpal tunnel syndrome) from using a uncomfortable mouse, the first thing you should do is replace your existing mouse. But you might not be aware of all the different types of mice that could be helpful in such a situation.

To help you, we have put together this guide on the best ergonomic mouse for wrist pain. After reading this post, you will understand the problem more clearly and find a mouse for wrist pain that suits your condition.

Reasons for wrist pain and Carpal Tunnel Syndrome form use of mice

1. A flat mouse could cause wrist pain if used for a long time and several hours every day. This wrist pain could expand to the shoulders and forearm too.

2. Carpal tunnel problem is caused when pressure is put on the nerve of your wrist. CTS is the worst condition of the wrist pain problem due to the extensive use of a flat mouse.

Below are symptoms of carpal tunnel you could feel in your hand and forearm

i. Tingling sensations
ii. Numbing and pain
iii. Inflammation

An ergonomic mouse could be helpful to avoid strain or fatigue on the wrist. To understand why an ergonomic vertical mouse is good for wrist pain, we must find the difference between an ergonomic and flat mouse.

The below table shows the difference between an ergonomic mouse and a standard mouse.

Flat Mouse

Ergonomic Mouse

When you hold a flat mouse, it causes your forearm to twist, which puts stress on the wrist.

An ergonomic vertical mouse keeps your hand in a neutral position.

To use a standard mouse, you have to grip the mouse tightly.

Vertical mice require less grip strength; as a result you put less strain on your wrist.

Working for several hours each day with a flat mouse could lead to CTS and RSI related problems.

Help avoid RSI, fatigue and you can prevent carpal tunnel syndrome

An ergonomic trackball mouse does not require you to move your hand to move the cursor; instead, you use your fingers to move the cursor.

Ergonomic mice have all the features that flat mice have. You can adjust the DPI to suit your needs and program the buttons to trigger a specific action.

These computer mice also provide precision cursor tracking, required for creative work like CAD designs or photo editing. You can also play games with slanted or trackball mice.

1. Kensington Expert – Best trackball mouse for wrist pain

This Kensington Expert Trackball Wireless mouse is ergonomically engineered to decrease tiredness and wrist strain, making it suitable for those suffering from arthritis or carpal tunnel syndrome. By just moving the trackball with your fingers, you may enjoy smooth, precise cursor control and a comfortable and accurate motion.

You may swiftly switch between programmes by using dedicated buttons, or you can use the scroll ring to easily scroll up and down on web pages or spreadsheets.

A removable, ergonomic wrist rest pad relieves hand and pain in the wrist while working, and the ambidextrous design allows users to use either hand to operate the mouse. If you ask me Kensington Expert Trackball is the best ergonomic mouse for wrist pain you can end your search here.

 You can assign different actions each button can perform based on your convenience. You can also adjust the cursor tracking speed.


Specifications in a Glance:

  • Connectivity: Dual connectivity, Bluetooth, and wireless 2.4 GHz
  • Design: Ergonomic Trackball
  • Sensor: Optical sensor
  • Scroll Wheel: Scroll Ring
  • Weight: 453.02
  • Hand Orientation: Ambidextrous
  • Power: AA battery
  • RGB: No
  • Buttons: 4
  • OS compatibility: Windows OS, above, macOS 10.9, macOS Sierra 10.12
  • Easy to use very comfortable mouse design

  • Detachable wrist rest

  • Programmable buttons

  • Well-build and durable

  • Dual wireless connectivity

  • Not all users can get comfortable with trackball

  • Not suitable as gaming mouse

  • Not easy to travel with


Kensington Expert is one of the most successful trackball mice in the market with lots of happy customers. The design, size, and comfort of use are remarkable.

It does take more space on the desk with a wrist support pad and is a bit heavier than usual mice, but it serves the purpose well, and your wrist would be stress-free. You can switch the trackball between hands, allowing one hand to rest if you work for long hours and require mouse use as a part of work.


Buy Button

eBay Buy Button

2. Logitech MX Vertical – Best Ergonomic Vertical Mouse

Logitech MX Vertical Wireless Mouse is a top-of-the-line designed to maximise comfort. Its advanced ergonomic design reduces muscle strain, fatigue, and numbness caused due to repetitive movement of the wrist. It’s the best vertical mouse built after research.

MX Vertical mice are highly accurate and responsive, allowing users to use the it accurately and quickly in any environment. Its cross computer control lets you seamlessly navigate on three computers.

You can enjoy precise cursor movement with a 4000 DPI high-precision sensor for tracking accuracy. These wireless mice are designed with a contoured design that feels comfortable in hand, even during extended use.

MX vertical mouse has a tilt of about 57 degrees, and on the side, the scoop thumb can rest, as you can see in the image. This vertical mouse is easy to adapt because most of the arrangement of the buttons is just like a flat mouse.

Specifications in a Glance:

  • Connectivity: Wired, Bluetooth, and WirelessLogitech_MX_Vertical_Wireless_Mouse_-_for_strain_free_wrist
  • Design: Ergonomic vertical style
  • Sensor: Logitech high-precision sensor
  • Scroll Wheel: yes
  • Weight: 135 g
  • Hand Orientation: Right-Hand
  • Power: Rechargeable Li-Po battery (240 mAh)
  • RGB: No
  • Buttons: 4, programmable
  • OS compatibility: Windows, macOS, iPadOS, macOS
  • Multi-device connectivity, up to 3

  • Optimal performance

  • Ergonomic handshake position

  • Durable and feels good when you hold it

  • Not easy to carry around despite the wireless capability

  • Will take some time to familiarize


Despite its massive appearance, it is surprisingly lighter than you may imagine. It can accommodate hands of different sizes. You can configure the mouse buttons with logitech flow software which is easy to use.

It can be linked to three different devices. Provide help to relieve wrist pain and CTS condition and is recommended as the best ergonomic wireless mouse for wrist pain by thusnds of users. It’s one of the best vertical ergonomic mouse you can have.

Buy Button

eBay Buy Button


3. Logitech ERGO M575 – Best Thumb Trackball Mouse for Wrist Pain

The Logitech MX ERGO M575 mouse is designed to suit your hand comfortably with a simple and easy-to-use design.

You can put your hand on the mouse the way you place it on the normal mouse; except for cursor tracking, you have to use a thumb trackball.

This mouse has a smooth and pleasant surface texture. With the thumb trackball, cursor control is effective and precise.

This mouse comes in black and white colours, will perform well in any setting and is gentle on the wrist and forearm because it does not require hand movements.

Because the ERGO M575 is Bluetooth and 2.4 GHz compatible, you can effortlessly pair it with your laptop or desktop computer, with no drop-offs within a 33-foot range.

ERGO M575 allows users to move the cursor across the screen as easily as if they were using a regular mouse. The trackball is positioned at an angle that allows for easy thumb reach.

Specifications in a Glance:

  • Connectivity: Dual Bluetooth and 2.4 GHz
  • logitech-ergo-m575 mouse for wrist painDesign: Ergonomic shape
  • Sensor: Logitech Advanced Optical Tracking, 400-2000 DPI
  • Scroll Wheel: 2-wheel with middle click
  • Weight: 145 g
  • Hand Orientation: Right-Hand
  • Power: 1 x AA battery (included)
  • RGB: NO fancy Lights
  • Buttons: 5
  • OS compatibility: Windows OS macOS 10.15 or later iPad OS 14 or later Linux®
  • Sturdily built

  • Exceptionally comfortable for wrist

  • Multi-OS compatible
  • Bulky in size




The Logitech ERGO M575 is one of the most advanced mouse on the market. You can choose between two skin colours: white and graphite. It has a significantly smoother trackball than its predecessor, the Logitech M570. On the bottom, they’ve added a single grip pad. Its ergonomics are well-designed to keep your wrist in a more natural position.

if you leave the mouse idle for a certain time it will activate power saving mode to save battery power.

It’s a little heavier and bigger than the previous Logitech M570 model. It is without a doubt the greatest mouse for wrist pain.
Thumb trackball is not for everyone; it takes some time to get used to.

Buy Button

eBay Buy Button


4. Swiftpoint ProPoint – Best ergonomic mouse for small hands 

Swiftpoint ProPoint is an unusual type of mouse; this ergonomic mouse provides a constant and comfortable pen-style feel when you hold it. The vertical grip sheath design offers a natural and constant pen hold/grip for reduced hand and wrist stress and protection against repetitive strain injury, commonly associated with flat mice.

This ergonomic vertical pen-style grip relieves pain by aligning your palm and wrist and straightening your fingers and forearm.

SwiftPoint_ProPoint - Gesture_mouse_for_hand_pain

The ProPoint mouse includes built-in health software that can measure hand movements to determine when you need to take a break. It sends you an alert so you can rest your hand.

The ProPoint mouse can be converted into a full-featured presentation clicker. Smooth cursor control and scroll wheel functionality allow you to easily navigate your slides.

It can also function as an air mouse, as a virtual laser mouse pointer, spotlight, magnifier, annotation tool, and is compatible with mark-up tools. It’s the best mouse for wrist pain because all of the functions are neatly combined in a tiny ergonomic mouse.

Specifications in a Glance:

    • Connectivity: Bluetooth 4.0
    • Design: Ergonomic pen grip
    • Sensor: 1800 DPI Optical sensor
    • Scroll Wheel: soft-touch mechanical wheel
    • Weight: 24 g
    • Hand Orientation: Right-Hand
    • Power: Chargeable
    • RGB: No lights
    • Buttons: 3, programable
    • OS compatibility: Windows, MacOS, Android, iPadOS


  • Good for hand wrist pain relief

  • Easy to hold

  • 2-week battery life in one quick charge

  • Built-in Gyroscope for smooth zooming, panning, rotating

  • Work as an air mouse

  • Lightweight and portable

  • It takes time and patience to get used to it

  • A bit tricky to configure on Linux

SwiftPoint ProPoint - Mouse hold like a pen for comfort


Many things are well combined in this tiny mouse. Despite its small size, the battery life is impressive. Its small size makes it ideal for travel you can plug and play mouse easily.

It positions your hand in a neutral posture.  You hold it like a pen or pencil. The built-in health software notifies the user when it is time to take a break you can set the break time as you want. It also keeps track of stats, how many hours you have worked with it. Its definetley one of the best ergonomic mouse for wrist pain you can travel with.


Buy Button

eBay Buy Button


5. Microsoft Sculpt – Best Ergonomic Mouse for Gaming

The Microsoft Sculpt ergonomic horizontal mouse is unlike any other mouse you’ve used before. The advanced ergonomic features of the sculpt mouse, designed for comfort, give you precise control on any surface.

The sculpt mouse has a strong sensor that allows for precise and efficient mouse control, so you won’t miss anything using it. It can even be used without a mousepad and still provide excellent accuracy and control.


Sculpt mouse works well with the Microsoft Windows operating system. You can access the Windows start menu with a single click.

The Sculpt ergonomic mouse’s unique side-rounded design with seamless tilt improves wrist comfort while simplifying navigation. The first step toward good hand health is maintaining proper posture. That’s why it’s critical to have the right muse for the job.

Specifications in a Glance:

  • Connectivity: Wireless 2.4 GHz
  • Design: Ergonomic with thumb support
  • Sensor: Blue Track Sensor
  • Scroll Wheel: 4-way scroll
  • Weight: 155 g, (includes 2 AA batteries and receiver)
  • Hand Orientation: Right-Hand
  • Power: 2 AA batteries
  • RGB: No
  • Buttons: 3, not programmable
  • OS compatibility: Windows OS, Macintosh OS X v 10.7-10.9 , Android 3.2 and 4.2
  • Good for wrist pain or arthritis in the hands

  • Compact design

  • Plain buttery smooth scroll

  • The rubber materials on the thumb grip are awesome

  • Not suitable for hands that get sweaty while working

  • Bit heavy

  • No Bluetooth




The Sculpt mouse keeps your hand fingers in a neutral position, and the upper mouse body is meant to support the palm so you don’t stress them. There is a bend on the side for the supporting thumb. All of these features make it best gaming mouse for wrist pain.


Buy Button

eBay Buy Button

6. Kensington Orbit Trackball – Best Ergonomic Mouse for Carpal Tunnel Syndrome

A trackball moves the Kensington Orbit mouse’s cursor. The Orbit mouse has four adjustable mouse sensitivity levels that can be changed with a DPI switch.

This ergonomic model mouse makes navigating the computer screen easy. Its trackball tracking technology allows for high-precision cursor movement, allowing you to set the pointer where you want it quickly and accurately.

This mouse is suitable for both right and left-handed users. The Orbit offers a simple reverse scrolling feature that allows you to scan documents in any direction quickly. You can also change the scrolling speed to suit your needs.


It also includes programmable buttons for rapid access to application shortcuts and programmes while reducing finger movement. The trackball is positioned in the centre and elevated from the middle to relieve your wrist for added comfort.

Specifications in a Glance:

  • Connectivity: 2.4 GHz and Bluetooth 3.0
  • Design: Ergonomic, ambidextrous design
  • Sensor: Optical Sensor
  • Scroll Wheel: Scroll Ring
  • Weight:  NA
  • Hand Orientation: Right-Hand
  • Power: Chargeable
  • RGB: No
  • Buttons: 2
  • OS compatibility: Windows OS and Mac OS X
  • Comfy to use with any finger

  • Can be used with either hand

  • Dual wireless connectivity

  • Satisfying click

  • Detachable palm and wrist pad

  • Takes time to learn


It is a low-cost top ergonomic trackball mouse with high build quality. I would recommend it to anybody who have wrist pain or CTS. The good news is that you may use it with any hand and any finger.


Buy Button

eBay Buy Button


7. Evoluent Vertical D – Best Computer Mouse for Wrist Pain

The Evoluent VMDS Vertical Mouse D is an excellent way to improve your PC experience and the health of your wrist. Thanks to advanced sensor technology and ergonomic design, you’ll have hyper-precise control navigating a spreadsheet or playing a computer game. A strategically placed groove on the side of buttons maintains adequate finger space to rest. With its unique design, you’ll be able to enjoy faster and more precise control.

The Evoluent vertical mouse D is intended to alleviate wrist discomfort for users facing excessive wrist problems, tight forearm muscles, hand fatigue, or CTS when using traditional mice.

It’s one of the most successful ergonomic mice on the market, in my opinion, with thousands of satisfied customers. The design, size, and comfort of use are all outstanding.

You can programme your mouse with just a few clicks using the Evoluent Vertical Mouse Manager software. This software allows you to make macros out of an infinite number of gestures. These can then be assigned to the buttons on the Vertical mouse.


Specifications in a Glance:

  • Connectivity: Wired only
  • Design:  Ergonomic vertical mouse
  • Sensor: Laser Sensor
  • Scroll Wheel: 2-way scroll
  • Weight: NA
  • Hand Orientation:  Right-Hand
  • Power: Direct wire
  • RGB: No
  • Buttons: 6
  • OS compatibility: Windows OS and Mac OS 10.5 to 10.14 (update for 10.15 is under development.
  • Relaxing for wrist and forearm

  • Comforatble thumb rest

  • Customizable buttons

  • Keeps your forearm in a natural position

  • No wireless


Evoluent has been producing best ergonomic mice since 2002. Their design has evolved to make their product more comfortable and adaptable and promote a neutral wrist and forearm posture.

Taking breaks while using vertical mice to relax your fingers, particularly the pinky finger, is essential because you stress it the most.
It is highly recommended for wrist pain. It’s one of the best mice for wrist pain that has stood the test.

Buy Button

eBay Buy Button

8. J-Tech Digital Wired Mouse – Best Ergonomic Mouse for Wrist Pain

The J-Tech Digital vertical mouse is ergonomically designed for comfort and ease of use, with textured sides providing the grip that aids in the reduction of fatigue and repetitive stress wrist injuries. This mouse has six buttons well placed around the mouse for easy access.

The J-Tech Vertical’s compact body is designed with an ergonomic and comfortable design that allows users to access and navigate easily. This mouse has a detachable palm rest pad.

This mouse is extremely comfortable for users with weak hands, designed to fit your hand configuration.

The blue LED light illuminates the mouse’s outline. It has three DPI mouse sensitivity settings: 800, 1200, and 1600.


Specifications in a Glance:

  • Connectivity: Wired
  • Design: Ergonomic Vertical Mouse
  • Sensor: Optical Mouse, Adjustable DPI 600/1000/1600
  • Scroll Wheel: yes
  • Weight: 310g
  • Hand Orientation: Right-Hand
  • Power: Direct Wire
  • RGB: Blue light outlining of the mouse
  • Buttons: 6
  • OS compatibility: Windows OS, Linux, Mac OS X
  • The ergonomic design makes it easy to use in all arm positions

  • Adjustable DPI

  • Help relieve wrist pain

  • Matt finish skin

  • No wireless


J-Tech made a reasonable effort with this improved model, outperforming the previous design. It is appropriate for all hand sizes. It relieves stress on your wrist.

Compared to the previous model, they have moved the DPI button to the bottom of the mouse, which was previously on top of the mouse and easily accessible.

The mouse’s skin is plain, unlike the previous model’s textured skin. Overall, the new changes have made it more comfortable.

Buy Button

eBay Buy Button

Best mouse wrist rest

Below are couple of wrist support pads that could also help to relieve wrist pain in conjunction with ergonomic mouse.

SOUNDANCE Ergonomic Mouse Pad -Best mouse wrist rest for gaming

SOUNDANCE Ergonomic Mouse Pad is the solution to your computer mouse hand issues, provides ultimate comfort and relief for computer users. The mouse pad is designed to relieve CTS pain caused by repeated or prolonged use of the mouse. The ergonomic design of the mouse pad ensures optimum support for your wrist while you work at your computer. It features a non-slip PU gel base that prevents the mouse pad from sliding while you work with your mouse, reducing the risk of tripping falls.


Buy Button

eBay Buy Button


Ergonomic Arm Rest Adjustable Mouse Pad -Best mouse wrist rest for carpal tunnel

Ergonomic Arm Rest Adjustable Mouse Pad with Wrist Support Armrest Wrist Rest Attachment Arm Pad for Chair is a great combination of support and comfort. It gives a wrist support to the armrest while providing a comfortable resting place for your wrists. It is perfect product to keep your hands in perfect alignment and you will be able to use your computer comfortably without any pain. It has an ergonomic design that supports the natural angles of your wrist while offering ultimate comfort to your hand.

Ergonomic_Arm_Rest_Adjustable_Mouse_Pad for wrist pain

Buy Button

eBay Buy Button



Frequently Asked Questions

Are ergonomic mice suitable for wrist support?

Yes, ergonomic mice are designed to provide maximum comfort to the wrist.

How do you get wrist pain from mice?

Below are some of the possible reasons for wrist pain caused by a mouse.

  • Working or playing on the computer with a mouse for prolonged periods.
  • Your mouse does not fit comfortably in your hand.
  • Body posture is poor.
  • Mice who refuse to keep your hand in a neutral position.

What preventive measures you can take to avoid wrist pain from mouse use?

Below are some of the measures you can take to avoid pain in the wrist.

  • To avoid arm stretch, keep the mouse close to the keyboard; this keeps your wrist relaxed.
  • Take frequent breaks.
  • If you must use a flat mouse, choose one that is ambidextrous to use with both hands. If one hand becomes tired, you can use the other hand to rest the weary hand.
  • Don’t hold on to the mouse too tightly.

What is the reason for getting carpal tunnel syndrome from the mice?

The main reason for getting carpal tunnel problem is repeated wrist movement for prolonged hours. To avoid CTS you should use an ergonomic mouse.

 Why use an ergonomic mouse for wrist pain?

Below are some reasons to use an ergonomic mouse.

  • A conventional mouse with an ergonomic design keeps your hand in a neutral position.
  • Reduce extraneous muscle movement.
  • You don’t have to grip the ergonomic mouse tightly; this relieves pressure on the wrist.

Which mouse is the best for CTS?

The best mouse you can have for carpal tunnel syndrome is the Kensington Expert Trackball mouse because it minimizes wrist extension; you don’t have to drag the mouse to move the cursor. You can also use it with any hand. 

The second mouse I could recommend is Logitech MX Vertical because it takes the pressure away from the wrist and keeps your hand and forearm in a neutral position.



Share with someone you care - Tech and About

Leave a Reply